WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:cellular modified amino acid catabolic process       ID:GO:0042219
C=12; O=2; E=0.02; R=101.60; rawP=0.0002; adjP=0.0320
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000144908 NA ALDH1L1 aldehyde dehydrogenase 1 family, member L1 10840 ENSG00000144908


Database:biological process       Name:organic acid catabolic process       ID:GO:0016054
C=198; O=2; E=0.32; R=6.16; rawP=0.0414; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000144908 NA ALDH1L1 aldehyde dehydrogenase 1 family, member L1 10840 ENSG00000144908


Database:biological process       Name:single-organism catabolic process       ID:GO:0044712
C=259; O=2; E=0.42; R=4.71; rawP=0.0668; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000144908 NA ALDH1L1 aldehyde dehydrogenase 1 family, member L1 10840 ENSG00000144908


Database:biological process       Name:DNA conformation change       ID:GO:0071103
C=188; O=2; E=0.31; R=6.48; rawP=0.0377; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132740 NA IGHMBP2 immunoglobulin mu binding protein 2 3508 ENSG00000132740
2  ENSG00000186462 NA NAP1L2 nucleosome assembly protein 1-like 2 4674 ENSG00000186462


Database:biological process       Name:sulfur compound metabolic process       ID:GO:0006790
C=237; O=2; E=0.39; R=5.14; rawP=0.0571; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684


Database:biological process       Name:cell adhesion       ID:GO:0007155
C=954; O=4; E=1.57; R=2.56; rawP=0.0674; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
3  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
4  ENSG00000144061 NA NPHP1 nephronophthisis 1 (juvenile) 4867 ENSG00000144061


Database:biological process       Name:organic anion transport       ID:GO:0015711
C=264; O=2; E=0.43; R=4.62; rawP=0.0690; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
2  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923


Database:biological process       Name:sulfur compound biosynthetic process       ID:GO:0044272
C=116; O=2; E=0.19; R=10.51; rawP=0.0154; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684


Database:biological process       Name:biological adhesion       ID:GO:0022610
C=956; O=4; E=1.57; R=2.55; rawP=0.0678; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
3  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
4  ENSG00000144061 NA NPHP1 nephronophthisis 1 (juvenile) 4867 ENSG00000144061


Database:biological process       Name:carbohydrate biosynthetic process       ID:GO:0016051
C=167; O=2; E=0.27; R=7.30; rawP=0.0303; adjP=0.8492
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684
2  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864


Database:molecular function       Name:anion transmembrane transporter activity       ID:GO:0008509
C=247; O=3; E=0.36; R=8.44; rawP=0.0051; adjP=0.1015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
2  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
3  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:protein transporter activity       ID:GO:0008565
C=91; O=2; E=0.13; R=15.27; rawP=0.0075; adjP=0.1015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
2  ENSG00000100478 NA AP4S1 adaptor-related protein complex 4, sigma 1 subunit 11154 ENSG00000100478


Database:molecular function       Name:substrate-specific transporter activity       ID:GO:0022892
C=980; O=5; E=1.41; R=3.54; rawP=0.0113; adjP=0.1015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
2  ENSG00000100478 NA AP4S1 adaptor-related protein complex 4, sigma 1 subunit 11154 ENSG00000100478
3  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
4  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
5  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:calcium ion binding       ID:GO:0005509
C=668; O=4; E=0.96; R=4.16; rawP=0.0141; adjP=0.1015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000203965 NA EFCAB7 EF-hand calcium binding domain 7 84455 ENSG00000203965
3  ENSG00000163703 NA CRELD1 cysteine-rich with EGF-like domains 1 78987 ENSG00000163703
4  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864


Database:molecular function       Name:organic anion transmembrane transporter activity       ID:GO:0008514
C=114; O=2; E=0.16; R=12.19; rawP=0.0116; adjP=0.1015
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
2  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:transporter activity       ID:GO:0005215
C=1196; O=5; E=1.72; R=2.90; rawP=0.0250; adjP=0.1422
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
2  ENSG00000100478 NA AP4S1 adaptor-related protein complex 4, sigma 1 subunit 11154 ENSG00000100478
3  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
4  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
5  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:substrate-specific transmembrane transporter activity       ID:GO:0022891
C=845; O=4; E=1.22; R=3.29; rawP=0.0306; adjP=0.1422
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
2  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
3  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
4  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:carboxylic acid binding       ID:GO:0031406
C=195; O=2; E=0.28; R=7.13; rawP=0.0316; adjP=0.1422
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
2  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862


Database:molecular function       Name:transmembrane transporter activity       ID:GO:0022857
C=925; O=4; E=1.33; R=3.00; rawP=0.0408; adjP=0.1632
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
2  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
3  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
4  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:molecular function       Name:ion transmembrane transporter activity       ID:GO:0015075
C=786; O=3; E=1.13; R=2.65; rawP=0.1010; adjP=0.3636
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
2  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923
3  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:cellular component       Name:axoneme       ID:GO:0005930
C=70; O=2; E=0.09; R=21.18; rawP=0.0040; adjP=0.1880
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
2  ENSG00000144061 NA NPHP1 nephronophthisis 1 (juvenile) 4867 ENSG00000144061


Database:cellular component       Name:Golgi apparatus       ID:GO:0005794
C=1180; O=5; E=1.59; R=3.14; rawP=0.0186; adjP=0.3306
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684
2  ENSG00000133878 NA DUSP26 dual specificity phosphatase 26 (putative) 78986 ENSG00000133878
3  ENSG00000103051 NA COG4 component of oligomeric golgi complex 4 25839 ENSG00000103051
4  ENSG00000100478 NA AP4S1 adaptor-related protein complex 4, sigma 1 subunit 11154 ENSG00000100478
5  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:cellular component       Name:basolateral plasma membrane       ID:GO:0016323
C=167; O=2; E=0.23; R=8.88; rawP=0.0211; adjP=0.3306
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135525 NA MAP7 microtubule-associated protein 7 9053 ENSG00000135525
2  ENSG00000116885 NA OSCP1 organic solute carrier partner 1 127700 ENSG00000116885


Database:cellular component       Name:Golgi membrane       ID:GO:0000139
C=553; O=3; E=0.75; R=4.02; rawP=0.0371; adjP=0.4359
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684
2  ENSG00000103051 NA COG4 component of oligomeric golgi complex 4 25839 ENSG00000103051
3  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:cellular component       Name:Golgi apparatus part       ID:GO:0044431
C=672; O=3; E=0.91; R=3.31; rawP=0.0601; adjP=0.4708
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684
2  ENSG00000103051 NA COG4 component of oligomeric golgi complex 4 25839 ENSG00000103051
3  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060


Database:cellular component       Name:cell projection part       ID:GO:0044463
C=639; O=3; E=0.86; R=3.48; rawP=0.0532; adjP=0.4708
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132740 NA IGHMBP2 immunoglobulin mu binding protein 2 3508 ENSG00000132740
2  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
3  ENSG00000144061 NA NPHP1 nephronophthisis 1 (juvenile) 4867 ENSG00000144061


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=5; E=2.59; R=1.93; rawP=0.1084; adjP=0.4858
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135525 NA MAP7 microtubule-associated protein 7 9053 ENSG00000135525
2  ENSG00000116885 NA OSCP1 organic solute carrier partner 1 127700 ENSG00000116885
3  ENSG00000160862 NA AZGP1 alpha-2-glycoprotein 1, zinc-binding 563 ENSG00000160862
4  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
5  ENSG00000114923 NA SLC4A3 solute carrier family 4, anion exchanger, member 3 6508 ENSG00000114923


Database:cellular component       Name:cytoplasmic membrane-bounded vesicle       ID:GO:0016023
C=862; O=3; E=1.16; R=2.58; rawP=0.1077; adjP=0.4858
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
3  ENSG00000103196 NA CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 83716 ENSG00000103196


Database:cellular component       Name:membrane-bounded vesicle       ID:GO:0031988
C=883; O=3; E=1.19; R=2.52; rawP=0.1137; adjP=0.4858
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
3  ENSG00000103196 NA CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 83716 ENSG00000103196


Database:cellular component       Name:cytoplasmic part       ID:GO:0044444
C=6772; O=13; E=9.13; R=1.42; rawP=0.0769; adjP=0.4858
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000125810 NA CD93 CD93 molecule 22918 ENSG00000125810
2  ENSG00000133878 NA DUSP26 dual specificity phosphatase 26 (putative) 78986 ENSG00000133878
3  ENSG00000103051 NA COG4 component of oligomeric golgi complex 4 25839 ENSG00000103051
4  ENSG00000100478 NA AP4S1 adaptor-related protein complex 4, sigma 1 subunit 11154 ENSG00000100478
5  ENSG00000004864 NA SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 10165 ENSG00000004864
6  ENSG00000144908 NA ALDH1L1 aldehyde dehydrogenase 1 family, member L1 10840 ENSG00000144908
7  ENSG00000205060 NA SLC35B4 solute carrier family 35, member B4 84912 ENSG00000205060
8  ENSG00000135525 NA MAP7 microtubule-associated protein 7 9053 ENSG00000135525
9  ENSG00000160200 NA CBS cystathionine-beta-synthase 875 ENSG00000160200
10  ENSG00000174684 NA B3GNT1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 11041 ENSG00000174684
11  ENSG00000096872 NA IFT74 intraflagellar transport 74 homolog (Chlamydomonas) 80173 ENSG00000096872
12  ENSG00000103196 NA CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 83716 ENSG00000103196
13  ENSG00000120334 NA CENPL centromere protein L 91687 ENSG00000120334




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).